I don’t know when this photo was taken, but I’m guessing 1940s. We’re on Vine Street here, looking north to the Hollywood Boulevard corner. On the right is the Brown Derby and past that the Taft Building, which held the offices of the Academy of Motion Picture Arts and Sciences from 1935 to 1945. On the left we can see the Plaza Hotel which at one point housed the It Café owned by the It Girl herself, Clara Bow (more pics on that at http://wp.me/p5XK3w-o3 )
Daniel Nauman says: This was taken sometime before mid-1938, when KNX moved to the new Columbia Square on Sunset.
Andie Paysinger says: The car in the right lane is a 1938 Ford Coupe.